Hepatic Vein Thrombosis in a COVID-19 Patient with Hereditary Thrombophilia: A Case Report

Authors

  • Georges Chedid, MD Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University
  • Rita Khoury, MD Division of Hematology/Oncology, Lebanese American University Medical Center – Rizk Hospital, Beirut, Lebanon
  • Hussein Noureldine, MD Gilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon
  • Jad Gerges Harb, MD Gilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon
  • Esther Tannoury, MD Department of Medical Imaging and Interventional Therapeutics, Lebanese American University Medical Center – Rizk Hospital, Beirut, Lebanon
  • Sahar Semaan, MD Department of Medical Imaging and Interventional Therapeutics, Lebanese American University Medical Center – Rizk Hospital, Beirut, Lebanon
  • Tamina Elias Risk, MD Department of Medical Imaging and Interventional Therapeutics, Lebanese American University Medical Center – Rizk Hospital, Beirut, Lebanon
  • Hady Ghanem, MD Division of Hematology/Oncology, Lebanese American University Medical Center – Rizk Hospital, Beirut, Lebanon

DOI:

https://doi.org/10.38179/ijcr.v3i1.120

Keywords:

Factor V Leiden, MTHFR mutation, thrombophilia, COVID-19, Case report

Abstract

Background: COVID-19 is an infection secondary to the novel SARS-COV-2 virus with a well-established increased risk for thrombotic events. However, the interaction between COVID-19 and other patient-specific hereditary or acquired thrombophilias remains a poorly explored area.

Case Presentation: We herein report a case of a 23-year-old Caucasian female with known risk factors for coagulopathy (smoking, oral contraceptives, anti-phospholipid (aPL) antibodies, heterozygous Factor V Leiden mutation, and homozygous methylenetetrahydrofolate reductase (MTHFR) mutation) who developed a Budd-Chiari syndrome after testing positive for COVID-19. To our knowledge, this is the first report of a case of splanchnic vein thrombosis in a COVID-19 patient with the above risk factors.

Conclusion: Such a presentation underscores the additional increased thrombotic risk attributed to COVID-19 infections in the setting of underlying hereditary or acquired thrombophilias.

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Axial CT scan images of the lower cuts of the chest (lung window) showing bilateral peripheral ground glass opacities associated with subtle interstitial intralobular septal thickening and lobular consolidation, typical for COVID-19 infection.

Published

2022-08-20

How to Cite

Chedid, G., Khoury, R., Noureldine, H. A., Gerges Harb, J., Tannoury, E., Semaan, S., Elias-Rizk, T., & Ghanem, H. (2022). Hepatic Vein Thrombosis in a COVID-19 Patient with Hereditary Thrombophilia: A Case Report. International Journal of Clinical Research, 3(1), 127-131. https://doi.org/10.38179/ijcr.v3i1.120

Issue

Vol. 3 No. 1 (2022): Volume 3, Issue 1

Section

Articles

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